ICD-10 Code G12.25 – Progressive spinal muscle atrophy (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Progressive spinal muscle atrophy is G12.25.
2026 ICD-10-CM Diagnosis Code G12.25 – Progressive spinal muscle atrophy

What it is

G12.25 identifies progressive spinal muscle atrophy, a disorder causing gradual degeneration of lower motor neurons in the spinal cord. It leads to progressive muscle weakness and wasting.

Clinical signs

Typical findings include slowly worsening weakness, muscle atrophy, and reduced reflexes. Clinical features vary; refer to documentation.

When to use this code

Use G12.25 when the provider documents progressive spinal muscle atrophy as the diagnosis. Apply it for confirmed cases of this specific motor neuron disorder, not for nonspecific weakness or undiagnosed neuromuscular symptoms.

Do not use for

Do not use this code for other spinal muscular atrophies, hereditary neuromuscular diseases, or muscle weakness without a documented diagnosis. Check documentation.

Coding tip

Confirm that the record states “progressive spinal muscle atrophy” specifically before assigning G12.25.

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