ICD-10 Code F78.A1 – SYNGAP1-related intellectual disability (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F78.A1 – SYNGAP1-related intellectual disability
What it is
F78.A1 identifies intellectual disability associated with SYNGAP1-related neurodevelopmental disorder. Use it when the diagnosis specifically links the cognitive impairment to a SYNGAP1 variant.
Clinical signs
Clinical features vary; refer to documentation. Commonly documented findings may include developmental delay, intellectual impairment, speech delay, and seizures, but the record should support the SYNGAP1-related diagnosis.
When to use this code
Use this code when the clinician documents SYNGAP1-related intellectual disability, or when genetic testing and specialist assessment clearly connect the intellectual disability to SYNGAP1. It is appropriate for confirmed cases in neurology, genetics, or developmental evaluations. Check documentation if the chart only states nonspecific developmental delay.
Do not use for
Do not use this code for unspecified intellectual disability or developmental delay without a documented SYNGAP1 association. Do not assign it when the genetic finding is absent, uncertain, or unrelated to the intellectual disability.
Coding tip
Capture the exact provider wording and any confirmed genetic result before assigning F78.A1.