ICD-10 Code F43.23 – Adjustment disorder with mixed anxiety and depressed mood (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F43.23 – Adjustment disorder with mixed anxiety and depressed mood
What it is
F43.23 identifies an adjustment disorder where a clear stressor is followed by both anxious and depressed mood symptoms. Use it when the reaction is out of proportion to the stressor and causes noticeable distress or impaired functioning.
Clinical signs
Clinical features vary; refer to documentation. Common findings include worry, nervousness, low mood, tearfulness, sleep disturbance, and trouble concentrating after an identifiable life stressor.
When to use this code
Use this code when the record documents mixed anxiety and depressed mood linked to a recent stressor, such as relationship, work, or health changes. The clinician should describe the adjustment reaction and its impact on daily functioning. Check documentation if the presentation is better explained by another mental disorder.
Do not use for
Do not use F43.23 for major depressive disorder, generalized anxiety disorder, or normal stress reactions without documented functional impairment. If the chart does not clearly show both anxiety and depressed mood, check documentation.
Coding tip
Confirm the stressor, symptom mix, and timing in the note before assigning F43.23.