ICD-10 Code F32.1 – Major depressive disorder, single episode, moderate (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F32.1 – Major depressive disorder, single episode, moderate
What it is
F32.1 identifies a single episode of major depressive disorder with moderate severity. Use it when the record shows one depressive episode, not recurrent depression or a different mood disorder.
Clinical signs
Typical findings include depressed mood, loss of interest, low energy, sleep or appetite change, and impaired concentration. Clinical features vary; refer to documentation for severity and duration.
When to use this code
Use F32.1 when the clinician documents major depressive disorder, single episode, moderate, or equivalent wording. It fits a first documented depressive episode with moderate functional impact. Confirm that the note does not describe recurrent episodes, remission, or a different depressive subtype.
Do not use for
Do not use this code for recurrent major depressive disorder, mild or severe single episodes, or bipolar depression. Check documentation if the diagnosis is uncertain or if another mood disorder is recorded.
Coding tip
Match the code to the documented episode type and severity, and verify that “single episode” is explicitly supported.