ICD-10 Code F18.280 – Inhalant dependence with inhalant-induced anxiety disorder (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Inhalant dependence with inhalant-induced anxiety disorder is F18.280.
2026 ICD-10-CM Diagnosis Code F18.280 – Inhalant dependence with inhalant-induced anxiety disorder

What it is

This code identifies inhalant dependence when the patient also has anxiety caused by inhalant use. It applies when both the substance use disorder and the substance-induced anxiety disorder are documented.

Clinical signs

Clinical features vary; refer to documentation. You may see compulsive inhalant use, inability to cut down, and anxiety symptoms that begin during or after inhalant use and are not better explained by another condition.

When to use this code

Use this code when the record clearly links inhalant dependence with an inhalant-induced anxiety disorder. It is appropriate when the clinician documents anxiety as substance-induced and ties it to the inhalant use disorder. Check documentation if the relationship is unclear.

Do not use for

Do not use this code for inhalant abuse, uncomplicated inhalant dependence, or anxiety disorder unrelated to inhalant use. If the anxiety cause is not documented, do not assume a substance-induced diagnosis.

Coding tip

Confirm both the dependence and the anxiety disorder are explicitly documented as inhalant-related before assigning F18.280.

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