ICD-10 Code F16.22 – Hallucinogen dependence with intoxication (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F16.22 – Hallucinogen dependence with intoxication
What it is
F16.22 identifies hallucinogen dependence when the patient is also intoxicated. Use it for documented dependence on hallucinogenic substances, with current acute effects from use.
Clinical signs
Clinical features vary; refer to documentation. Intoxication may include altered perception, impaired judgment, mood changes, or behavioral disturbance, alongside evidence of dependence.
When to use this code
Use this code when the record clearly states hallucinogen dependence and intoxication are both present. It may apply in emergency, inpatient, or behavioral health documentation when acute substance effects are noted with a dependence diagnosis.
If the note only documents use, abuse, or intoxication without dependence, check documentation before assigning F16.22. Code the documented substance and condition as written.
Do not use for
Do not use this code for hallucinogen intoxication alone or for dependence without intoxication. Do not assume the diagnosis from symptoms if the provider has not documented it.
Coding tip
Confirm both dependence and intoxication are explicitly stated in the provider record before assigning F16.22.