ICD-10 Code F16.21 – Hallucinogen dependence, in remission (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Hallucinogen dependence, in remission is F16.21.
2026 ICD-10-CM Diagnosis Code F16.21 – Hallucinogen dependence, in remission

What it is

This code identifies a documented history of hallucinogen dependence that is now in remission. Use it when the patient no longer meets active dependence criteria, but the condition remains clinically relevant.

Clinical signs

Current signs of dependence are absent or reduced enough that remission is documented. Clinical features vary; refer to documentation for the substance involved, duration of remission, and whether any residual use or craving is present.

When to use this code

Use this code when the record clearly states hallucinogen dependence is in remission, including early or sustained remission if specified. It may support ongoing behavioral health follow-up, past substance use history, or continuity of care. Do not infer remission without documentation.

Do not use for

Do not use for active hallucinogen dependence, uncomplicated use, abuse, or intoxication. If the chart only says “history of use” or the substance is not identified, check documentation.

Coding tip

Match the code to the exact provider wording and confirm that remission, not just abstinence, is documented.

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