ICD-10 Code F15.221 – Other Stimulant Dependence with Intoxication Delirium (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F15.221 – Other stimulant dependence with intoxication delirium
What it is
This code identifies stimulant dependence with delirium caused by intoxication. It applies when stimulant use has produced both a dependence pattern and an acute delirium state.
Clinical signs
Delirium usually presents as disturbed attention, confusion, and reduced awareness that develops during intoxication. Clinical features vary; refer to documentation for evidence of stimulant dependence and intoxication-related delirium.
When to use this code
Use F15.221 when the record clearly documents dependence on another stimulant and delirium linked to intoxication. Choose it when the provider links the delirium to stimulant use, not to withdrawal, another substance, or a medical condition. Check documentation if the stimulant type is not specified.
Do not use for
Do not use this code for stimulant intoxication without delirium or for dependence without an acute delirium episode. It is also incorrect when delirium has another documented cause.
Coding tip
Verify that both dependence and intoxication delirium are documented together before assigning this code.