ICD-10 Code F14.221 – Cocaine dependence with intoxication delirium (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F14.221 – Cocaine dependence with intoxication delirium
What it is
This code identifies cocaine dependence with delirium caused by intoxication. It means the patient has a cocaine use disorder and develops an acute confusional state during intoxication.
Clinical signs
Typical findings include disturbed attention, disorientation, altered awareness, and impaired thinking that are consistent with delirium. Clinical features vary; refer to documentation for the specific mental status changes and intoxication context.
When to use this code
Use this code when the record clearly links cocaine dependence to delirium occurring during intoxication. You should have documentation of both the dependence and the delirium, not just recent cocaine use. If the note does not specify intoxication delirium, check documentation.
Do not use for
Do not assign this code for cocaine use without dependence, or for delirium from another cause. Do not use it when the record only describes intoxication, withdrawal, or an unspecified mental disorder.
Coding tip
Verify that the provider documents both dependence and delirium as intoxication-related before selecting F14.221.