ICD-10 Code A04.2 – Enteroinvasive Escherichia coli infection (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Enteroinvasive Escherichia coli infection is A04.2.
2026 ICD-10-CM Diagnosis Code A04.2 – Enteroinvasive Escherichia coli infection

What it is

A04.2 identifies infection caused by enteroinvasive Escherichia coli, a diarrheal illness that affects the intestines. Use it when documentation names this specific organism or diagnosis.

Clinical signs

Clinical features can include diarrhea, abdominal cramping, fever, and sometimes blood or mucus in stool. Clinical features vary; refer to documentation.

When to use this code

Use A04.2 when the provider documents enteroinvasive E. coli infection, EIEC, or a confirmed diagnosis tied to this organism. It is appropriate when the record clearly links the gastrointestinal illness to E. coli invasion rather than a nonspecific infectious diarrhea. If the chart does not specify the organism, check documentation.

Do not use for

Do not use this code for other diarrheal infections, unspecified gastroenteritis, or noninfectious causes of diarrhea. If the organism is different or not stated, choose the documented diagnosis instead.

Coding tip

Code A04.2 only when the documentation supports enteroinvasive E. coli specifically, not just “E. coli” or “infectious diarrhea.”

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