ICD-10 Code F12.280 – Cannabis dependence with cannabis-induced anxiety disorder (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F12.280 – Cannabis dependence with cannabis-induced anxiety disorder
What it is
Use this code for a documented cannabis dependence disorder where anxiety symptoms are caused by cannabis use. It identifies both the substance use pattern and the substance-induced anxiety condition.
Clinical signs
Typical findings include problematic cannabis use with dependence features, along with anxiety that develops during or soon after cannabis use. Clinical features vary; refer to documentation.
When to use this code
Use F12.280 when the provider explicitly documents cannabis dependence and cannabis-induced anxiety disorder together. It may apply when the anxiety is assessed as substance-induced rather than a primary anxiety disorder. Check documentation if the record does not clearly link the anxiety to cannabis.
Do not use for
Do not use this code for cannabis use without dependence, or for anxiety disorder not attributed to cannabis. If the note only says anxiety with cannabis use, check documentation.
Coding tip
Code the substance-induced anxiety only when the causal relationship to cannabis is clearly documented.