ICD-10 Code F12.21 – Cannabis dependence, in remission (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F12.21 – Cannabis dependence, in remission
What it is
This code identifies cannabis dependence that is documented as being in remission. It means the patient has a history of dependence, but current records indicate the disorder is no longer active.
Clinical signs
Clinical features vary; refer to documentation. You may see a past pattern of compulsive cannabis use, tolerance, withdrawal, or impaired control, with remission noted in the chart.
When to use this code
Use this code when the provider documents cannabis dependence as “in remission,” “sustained remission,” or similar wording. It applies when the dependence is not currently active, but the diagnosis remains clinically relevant. Check the note for the remission status and any accompanying substance use diagnoses.
Do not use for
Do not use it for current cannabis dependence, cannabis abuse, or uncomplicated cannabis use. If the record does not clearly state remission, check documentation before assigning this code.
Coding tip
Code remission only when the provider explicitly documents it; do not infer it from abstinence alone.