ICD-10 Code E87.4 – Mixed disorder of acid-base balance (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Mixed disorder of acid-base balance is E87.4.
2026 ICD-10-CM Diagnosis Code E87.4 – Mixed disorder of acid-base balance

What it is

This code identifies a documented mixed acid-base disorder, meaning more than one acid-base process is present at the same time. It is used when the pattern cannot be described as a single, isolated imbalance.

Clinical signs

Clinical features vary; refer to documentation. Patients may show findings consistent with combined metabolic and respiratory disturbances, and the record should support that more than one acid-base abnormality is present.

When to use this code

Use E87.4 when the provider documents a mixed acid-base disorder, mixed acidosis, or mixed alkalosis. It may also apply when the chart clearly describes simultaneous opposing acid-base processes. If the documentation is unclear, check documentation before assigning the code.

Do not use for

Do not use this code for a single acid-base imbalance such as isolated acidosis or alkalosis. Do not assign it when the record only shows abnormal blood gas results without a documented mixed disorder.

Coding tip

Code only when the provider explicitly documents a mixed acid-base disorder or the chart clearly supports it.

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