ICD-10 Code E78.2 – Mixed hyperlipidemia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E78.2 – Mixed hyperlipidemia
What it is
Mixed hyperlipidemia means more than one blood lipid abnormality is present, usually involving elevated cholesterol and triglycerides. Use this code when the record identifies a mixed lipid disorder without a more specific subtype.
Clinical signs
Clinical features may be absent, and the condition is often found on laboratory testing. Documentation may note elevated total cholesterol, triglycerides, or combined dyslipidemia; clinical features vary, refer to documentation.
When to use this code
Use E78.2 when the provider documents mixed hyperlipidemia, mixed dyslipidemia, or a combined lipid disorder. Apply it when both cholesterol and triglyceride abnormalities are described and no more specific lipid code is supported. Check documentation if the note is unclear.
Do not use for
Do not use this code for isolated hypercholesterolemia, isolated hypertriglyceridemia, or pure lipid disorders with a more specific code. If the record does not clearly state a mixed pattern, check documentation.
Coding tip
Code from the provider’s documented diagnosis, not from lab results alone.