ICD-10 Code E75.24 – Niemann-Pick disease (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Niemann-Pick disease is E75.24.
2026 ICD-10-CM Diagnosis Code E75.24 – Niemann-Pick disease

What it is

E75.24 identifies Niemann-Pick disease, a hereditary lipid storage disorder. It is used when the record documents this specific diagnosis rather than another sphingolipidosis.

Clinical signs

Clinical features vary; refer to documentation. Common findings may include hepatosplenomegaly, neurologic involvement, and developmental delay, depending on the disease subtype.

When to use this code

Use E75.24 when the provider documents Niemann-Pick disease as the confirmed diagnosis. It is appropriate for encounters focused on evaluation, monitoring, or management of the disorder. If the note names a specific variant or subtype, code that documented condition if supported.

Do not use for

Do not use this code for suspected disease, family history, or general lipid disorders. Check documentation if the record instead identifies another inherited metabolic storage disease.

Coding tip

Code from the provider’s exact wording and confirm whether a subtype is specified before assigning E75.24.

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