ICD-10 Code E75.2 – Other sphingolipidosis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E75.2 – Other sphingolipidosis
What it is
E75.2 identifies sphingolipid storage disorders that do not fit a more specific ICD-10-CM diagnosis. Use it for inherited conditions involving abnormal breakdown and accumulation of sphingolipids. Check documentation for the exact disorder named.
Clinical signs
Clinical features vary; refer to documentation. Common findings in sphingolipidosis may include progressive neurologic decline, organ enlargement, or developmental delay, depending on the specific disorder.
When to use this code
Use E75.2 when the provider documents a sphingolipidosis but does not name a more specific subtype. It also applies when the record states an “other” sphingolipid storage disorder or an unspecified sphingolipid metabolism condition. Verify that the diagnosis is confirmed or clearly assessed.
Do not use for
Do not use this code when the chart identifies a specific sphingolipidosis with its own ICD-10-CM code. Avoid using it for general lipid disorders or metabolic diseases unrelated to sphingolipid storage. Check documentation.
Coding tip
Code the most specific sphingolipidosis documented; reserve E75.2 for “other” or unclassified cases only.