ICD-10 Code E24.2 – Drug-induced Cushing’s syndrome (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E24.2 – Drug-induced Cushing’s syndrome
What it is
This code identifies Cushing’s syndrome caused by medication or other exogenous steroid exposure. Use it when the patient’s cortisol excess is linked to drug use rather than an endogenous endocrine disorder.
Clinical signs
Common findings include central weight gain, facial rounding, skin thinning, easy bruising, and muscle weakness. Clinical features vary; refer to documentation, especially when the record links the syndrome to corticosteroid therapy.
When to use this code
Use E24.2 when the provider documents Cushing’s syndrome due to drugs, such as long-term corticosteroid exposure. It also fits when the note clearly states steroid-induced hypercortisolism or medication-related Cushingoid changes. Check documentation if the cause is not explicit.
Do not use for
Do not use this code for endogenous Cushing’s syndrome, pituitary disease, or adrenal tumors. If the record only mentions steroid use without Cushing’s syndrome, this code is not appropriate.
Coding tip
Confirm the causal link in the provider’s note and code the underlying drug exposure when documented.