ICD-10 Code E24.0 – Pituitary-dependent Cushing’s disease (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Pituitary-dependent Cushing’s disease is E24.0.
2026 ICD-10-CM Diagnosis Code E24.0 – Pituitary-dependent Cushing’s disease

What it is

E24.0 identifies Cushing’s disease caused by a pituitary source of excess adrenocorticotropic hormone. Use it when documentation states pituitary-dependent hypercortisolism or a pituitary adenoma driving Cushing syndrome.

Clinical signs

Typical findings include features of cortisol excess such as central weight gain, facial rounding, skin thinning, easy bruising, and muscle weakness. Clinical features vary; refer to documentation.

When to use this code

Use this code when the provider documents Cushing’s disease, pituitary-dependent Cushing syndrome, or ACTH-secreting pituitary adenoma. It applies when the pituitary is the stated source of the disorder. If the record only says Cushing syndrome without a cause, check documentation.

Do not use for

Do not use E24.0 for Cushing syndrome from adrenal disease, exogenous steroid use, or unspecified hypercortisolism. Check documentation if the pituitary source is not clearly stated.

Coding tip

Code E24.0 only when the provider links the condition to a pituitary cause; otherwise, query for clarification.

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