ICD-10 Code E09.341 – Drug or chemical induced diabetes mellitus with severe nonproliferative diabetic retinopathy with macular edema (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Drug or chemical induced diabetes mellitus with severe nonproliferative diabetic retinopathy with macular edema is E09.341.
2026 ICD-10-CM Diagnosis Code E09.341 – Drug or chemical induced diabetes mellitus with severe nonproliferative diabetic retinopathy with macular edema

What it is

This code identifies diabetes caused by a drug or chemical, complicated by severe nonproliferative diabetic retinopathy and macular edema in the same eye. Use it when the record links the diabetes to an external substance and documents the eye findings.

Clinical signs

Clinical features vary; refer to documentation. Standard references describe severe nonproliferative retinopathy as advanced retinal vessel damage, and macular edema as swelling in the central retina that can affect vision.

When to use this code

Use E09.341 when the provider documents drug- or chemical-induced diabetes and specifies severe nonproliferative diabetic retinopathy with macular edema. You should also confirm laterality and that the eye condition is tied to the diabetes diagnosis in the note.

If the record does not clearly identify the causative substance or the diabetic eye complication, check documentation before coding. Code only when both the diabetes type and the retinal complication are supported.

Do not use for

Do not use this code for diabetes mellitus not caused by a drug or chemical, or for retinopathy without macular edema. If the chart says proliferative disease, unspecified retinopathy, or no eye involvement, choose a different code.

Coding tip

Verify the medication or chemical cause and the exact retinopathy severity before assigning E09.341.

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