ICD-10 Code E08.43 – Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy is E08.43.
2026 ICD-10-CM Diagnosis Code E08.43 – Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy

What it is

This code identifies diabetes mellitus caused by another underlying condition, with diabetic autonomic polyneuropathy. It indicates nerve damage affecting involuntary body functions, such as digestion, heart rate, or bladder control, in the setting of secondary diabetes.

Clinical signs

Clinical features vary; refer to documentation. Typical findings may include autonomic nerve dysfunction with symptoms such as abnormal sweating, gastrointestinal motility problems, orthostatic symptoms, or urinary dysfunction when attributed to diabetic neuropathy.

When to use this code

Use this code when the record clearly links diabetes to an underlying condition and documents autonomic polyneuropathy as a diabetic complication. You should also confirm the diabetes is secondary, not type 1 or type 2. If the provider documents the underlying cause, code it separately when instructed.

Do not use for

Do not use this code for primary diabetes, non-diabetic autonomic neuropathy, or diabetic peripheral neuropathy without autonomic involvement. Check documentation if the record does not clearly state the relationship to an underlying condition.

Coding tip

Verify both the secondary cause of diabetes and the autonomic neuropathy connection before assigning E08.43.

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