ICD-10 Code D84.82 – Immunodeficiency due to drugs and external causes (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D84.82 – Immunodeficiency due to drugs and external causes
What it is
This code identifies an acquired immune deficiency caused by medications or other external factors. It is used when the weakened immune state is documented as secondary to an outside cause, not a primary immune disorder.
Clinical signs
Clinical features vary; refer to documentation. Common charted findings may include recurrent or unusual infections, poor immune response, or a stated diagnosis of immunodeficiency linked to a drug or external exposure.
When to use this code
Use D84.82 when the provider documents immunodeficiency due to a medication, chemical exposure, or another external cause. Apply it when the record clearly ties the immune deficit to that cause and not to an inherited condition.
If the cause is not specified, check documentation before assigning the code. You should also confirm whether the record describes a different immune disorder that needs another code.
Do not use for
Do not use this code for primary or congenital immunodeficiency disorders. Do not use it when the chart only notes infection risk, immunosuppression, or an unspecified immune problem without a documented external cause.
Coding tip
Link the diagnosis to the documented external cause in the record, and query when the cause of immunodeficiency is unclear.