ICD-10 Code D73.81 – Neutropenic splenomegaly (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D73.81 – Neutropenic splenomegaly
What it is
D73.81 identifies splenomegaly documented as neutropenic splenomegaly. Use it when the spleen is enlarged and the record specifically links the finding to neutropenia or a neutropenic state.
Clinical signs
Clinical features vary; refer to documentation. Typical findings may include an enlarged spleen on exam or imaging, with evidence of neutropenia noted in the chart.
When to use this code
Use this code when the provider documents neutropenic splenomegaly, or clearly states splenomegaly associated with neutropenia. It may appear in records for patients being evaluated for hematologic disease, infection risk, or other causes of low neutrophil counts. Check documentation if the relationship is not explicit.
Do not use for
Do not use this code for splenomegaly without neutropenia, or for neutropenia without documented splenic enlargement. If the record only says “enlarged spleen,” code the documented condition instead.
Coding tip
Confirm that both neutropenia and splenomegaly are documented together before assigning D73.81.