ICD-10 Code D60 – Acquired pure red cell aplasia [erythroblastopenia] (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D60 – Acquired pure red cell aplasia [erythroblastopenia]
What it is
D60 identifies acquired pure red cell aplasia, a disorder where the bone marrow makes too few red blood cell precursors. It causes anemia because red cell production is selectively suppressed while other cell lines are usually preserved.
Clinical signs
Typical findings include fatigue, pallor, and other signs of anemia. Clinical features vary; refer to documentation for evidence of reticulocytopenia, marrow erythroid hypoplasia, or an acquired cause such as autoimmune disease, infection, or medication exposure.
When to use this code
Use D60 when the record clearly states acquired pure red cell aplasia or erythroblastopenia. It also fits confirmed cases in which the clinician documents selective red cell aplasia without another more specific underlying diagnosis being coded instead.
Review the chart for whether the condition is acquired rather than congenital. If the note only says anemia, bone marrow failure, or pancytopenia, check documentation before assigning D60.
Do not use for
Do not use D60 for nonspecific anemia, aplastic anemia, or pancytopenia. Also avoid it when the chart describes congenital pure red cell aplasia or another clearly documented cause that should be coded separately.
Coding tip
Code D60 only when the provider documents acquired pure red cell aplasia explicitly; otherwise, check documentation and code the stated anemia type.