ICD-10 Code D48.19 – Other specified neoplasm of uncertain behavior of connective and other soft tissue (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other specified neoplasm of uncertain behavior of connective and other soft tissue is D48.19.
2026 ICD-10-CM Diagnosis Code D48.19 – Other specified neoplasm of uncertain behavior of connective and other soft tissue

What it is

This code identifies a growth in connective or soft tissue whose behavior is uncertain, but it does not fit a more specific ICD-10 category. Use it when the record documents a specified soft-tissue neoplasm and pathology or clinical assessment has not confirmed benign or malignant behavior.

Clinical signs

Clinical features vary; refer to documentation. Findings may include a palpable mass, localized swelling, or imaging showing a soft-tissue lesion, but the key point is uncertainty about biologic behavior.

When to use this code

Use D48.19 when the provider documents an unspecified or otherwise classified soft-tissue neoplasm of uncertain behavior involving connective tissue, fascia, tendon, muscle, or similar structures. It is appropriate when pathology, imaging, or clinical notes support a neoplasm, but the record does not establish malignancy or a benign diagnosis.

Check documentation if the site is not clearly connective or soft tissue, or if the lesion is better described by another code. Code only what the provider states.

Do not use for

Do not use this code for confirmed malignant tumors, benign neoplasms, or inflammatory masses. If the documentation names a more specific neoplasm code, use that code instead.

Coding tip

Query the provider when the chart says “mass” or “lesion” but does not clearly state uncertain neoplasm of soft tissue.

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