ICD-10 Code D47.Z1 – Post-transplant lymphoproliferative disorder (PTLD) (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D47.Z1 – Post-transplant lymphoproliferative disorder (PTLD)
What it is
D47.Z1 identifies post-transplant lymphoproliferative disorder, a lymphoid proliferation that develops after organ or stem cell transplantation. It is linked to immunosuppression and may range from benign-appearing growth to aggressive lymphoma.
Clinical signs
Clinical features vary; refer to documentation. Common findings include unexplained lymphadenopathy, fever, weight loss, organ dysfunction, or mass lesions in transplanted or extranodal sites.
When to use this code
Use D47.Z1 when the provider documents PTLD or post-transplant lymphoproliferative disorder as the diagnosis. Code it for confirmed cases in a transplant recipient, whether the presentation is nodal, extranodal, or involves the graft. If the record only says “lymphoma” or “lymphoproliferative disorder” without PTLD, check documentation.
Do not use for
Do not use this code for routine post-transplant follow-up, rejection, or nonspecific lymphadenopathy without a documented PTLD diagnosis. If the condition is another lymphoma or a reactive process, choose the more specific documented code.
Coding tip
Confirm the transplant history and the provider’s exact wording before assigning D47.Z1.