ICD-10 Code A41.81 – Sepsis due to Enterococcus (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Sepsis due to Enterococcus is A41.81.
2026 ICD-10-CM Diagnosis Code A41.81 – Sepsis due to Enterococcus

What it is

A41.81 identifies sepsis caused by Enterococcus infection. Use it when the record clearly links the bloodstream infection and systemic response to Enterococcus.

Clinical signs

Clinical features may include fever, chills, altered mental status, low blood pressure, or other signs of systemic infection. Clinical features vary; refer to documentation.

When to use this code

Use A41.81 when the provider documents sepsis due to Enterococcus, or when the organism is identified as the cause of sepsis. You should code it from the final diagnosis, discharge summary, or equivalent signed documentation. If the record only shows Enterococcus infection without sepsis, this code is not appropriate.

Do not use for

Do not use this code for simple Enterococcus colonization, localized infection, or bacteremia without sepsis. Check documentation when the note is unclear about whether sepsis is present.

Coding tip

Confirm that the organism and sepsis are both documented before assigning A41.81.

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