ICD-10 Code A41.4 – Sepsis due to anaerobes (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code A41.4 – Sepsis due to anaerobes
What it is
A41.4 identifies sepsis caused by anaerobic bacteria. Use it when the record documents sepsis and specifically links the infection to anaerobes.
Clinical signs
Clinical features vary; refer to documentation. Sepsis commonly includes systemic infection with organ dysfunction, and the source organism is recorded as anaerobic bacteria.
When to use this code
Use A41.4 when the provider documents sepsis due to anaerobes or an anaerobic organism as the cause. It may also apply when the note clearly identifies an anaerobic infection with sepsis. If the causal organism is not specified, check documentation before coding.
Do not use for
Do not use this code for localized anaerobic infection without sepsis. Do not assign it when sepsis is documented but the organism is not identified as anaerobic.
Coding tip
Look for explicit linkage between sepsis and anaerobes in the provider note before assigning A41.4.