ICD-10 Code A41.2 – Sepsis due to unspecified staphylococcus (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Sepsis due to unspecified staphylococcus is A41.2.
2026 ICD-10-CM Diagnosis Code A41.2 – Sepsis due to unspecified staphylococcus

What it is

This code identifies sepsis caused by staphylococcus when the specific species is not documented. Use it for a systemic infection with a presumed or confirmed staphylococcal source that is otherwise unspecified.

Clinical signs

Clinical features vary; refer to documentation. Typical sepsis findings may include fever or hypothermia, altered mental status, tachycardia, and signs of organ dysfunction, with staphylococcal infection noted as the cause.

When to use this code

Use A41.2 when the provider documents sepsis due to unspecified staphylococcus and does not name a more specific organism. It is appropriate for confirmed or clinically diagnosed sepsis tied to staphylococcal infection. Check documentation if the record only states bacteremia, infection, or suspected sepsis.

Do not use for

Do not use this code for sepsis due to a specified staphylococcal species when a more precise code is documented. Do not assign it for localized staphylococcal infection without sepsis.

Coding tip

Code the organism exactly as documented, and query if the record says staphylococcus but does not clearly support sepsis.

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