ICD-10 Code A41.0 – Sepsis due to Staphylococcus aureus (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Sepsis due to Staphylococcus aureus is A41.0.
2026 ICD-10-CM Diagnosis Code A41.0 – Sepsis due to Staphylococcus aureus

What it is

A41.0 identifies sepsis caused by Staphylococcus aureus. Use it when the record shows a systemic infection due to this organism, not just a localized staphylococcal infection.

Clinical signs

Clinical features vary; refer to documentation. Sepsis is typically documented as infection with systemic illness, and the source organism is Staphylococcus aureus.

When to use this code

Use A41.0 when the provider documents sepsis due to Staphylococcus aureus, or clearly links sepsis to that organism. Code any documented associated infection or organ dysfunction separately when instructed by ICD-10-CM guidelines. If the organism is not confirmed, check documentation.

Do not use for

Do not use this code for localized staphylococcal infections without sepsis, or for sepsis caused by another organism. If the chart only says “staph infection” without sepsis, this code is not appropriate.

Coding tip

Confirm the provider’s organism-specific wording before assigning A41.0, and code the documented infection source as directed.

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