ICD-10 Code C95.92 – Leukemia, unspecified, in relapse (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C95.92 – Leukemia, unspecified, in relapse
What it is
This code identifies leukemia that has returned after a period of remission, when the specific leukemia type is not documented. Use it when the record confirms relapse but does not name the subtype.
Clinical signs
Clinical features vary; refer to documentation. Relapse is usually supported by evidence of recurrent leukemia in the marrow, blood, or other involved sites after prior remission.
When to use this code
Use C95.92 when the clinician documents recurrent leukemia and the subtype is not specified. It also fits cases where prior leukemia is known, but current notes only state “relapse,” “recurrent,” or “returned leukemia.”
If the chart names a specific leukemia type, code that more precise diagnosis instead. Check documentation for whether the relapse is confirmed, suspected, or still under evaluation.
Do not use for
Do not use this code for leukemia in remission, history of leukemia, or a newly diagnosed leukemia without relapse. Do not use it when a specific leukemia subtype is documented.
Coding tip
Code the relapse only when the provider clearly documents recurrence, and always look for a more specific leukemia type before defaulting to unspecified.