ICD-10 Code C95.12 – Chronic leukemia of unspecified cell type, in relapse (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C95.12 – Chronic leukemia of unspecified cell type, in relapse
What it is
C95.12 identifies chronic leukemia when the cell type is not specified and the disease has returned after a period of remission. Use it when documentation clearly states relapse or recurrence.
Clinical signs
Clinical features vary; refer to documentation. Commonly, relapse is supported by recurrent abnormal blood counts, marrow involvement, or renewed leukemia findings after prior response.
When to use this code
Use C95.12 when the provider documents chronic leukemia, unspecified cell type, as relapsed, recurrent, or in relapse. It applies after a prior remission or improvement, when the current encounter is for active disease again. Check documentation if the leukemia subtype is later identified.
Do not use for
Do not use this code for leukemia in remission, history of leukemia, or an acute leukemia diagnosis. If the cell type or subtype is specified, code that documented type instead.
Coding tip
Confirm both chronic status and relapse wording in the record before assigning C95.12.