ICD-10 Code C06.0 – Malignant neoplasm of cheek mucosa (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Malignant neoplasm of cheek mucosa is C06.0.
2026 ICD-10-CM Diagnosis Code C06.0 – Malignant neoplasm of cheek mucosa

What it is

C06.0 identifies a malignant tumor arising in the mucosal lining of the cheek, also called the buccal mucosa. Use it when documentation specifies cancer of the inner cheek.

Clinical signs

Findings may include a persistent oral ulcer, mass, pain, bleeding, or difficulty chewing. Clinical features vary; refer to documentation and pathology when available.

When to use this code

Use C06.0 when the provider documents primary cancer of the cheek mucosa, including biopsy-confirmed malignant neoplasm of the buccal mucosa. It may also apply when the record clearly localizes the tumor to the inner cheek. If the site is unclear, check documentation.

Do not use for

Do not use this code for benign oral lesions, inflammatory cheek conditions, or cancers of adjacent oral sites such as the lip, gum, or tongue unless the cheek mucosa is specifically documented.

Coding tip

Code the exact anatomic site stated in the note; if “cheek” is mentioned without mucosal involvement, verify the location before assigning C06.0.

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