ICD-10 Code J43.2 – Centrilobular Emphysema (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code J43.2 – Centrilobular emphysema
What it is
Centrilobular emphysema is a form of COPD that mainly affects the central parts of the lung lobules, usually in the upper lungs. It reflects destruction of air sacs and loss of elastic recoil.
Clinical signs
Common findings include progressive shortness of breath, reduced breath sounds, and hyperinflation on imaging. Clinical features vary; refer to documentation.
When to use this code
Use J43.2 when the provider documents centrilobular emphysema or CT, chest imaging, or pulmonary evaluation clearly identifies this subtype. It is appropriate when the record distinguishes it from other emphysema patterns. Check documentation if COPD is present but the emphysema type is not specified.
Do not use for
Do not use this code for emphysema that is not specified as centrilobular, or when documentation only states COPD without subtype detail. Do not assume the diagnosis from smoking history alone.
Coding tip
Code the documented emphysema subtype exactly as recorded, and query if the note mentions emphysema without naming the pattern.