ICD-10 Code I42.3 – Endomyocardial (eosinophilic) disease (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Endomyocardial (eosinophilic) disease is I42.3.
2026 ICD-10-CM Diagnosis Code I42.3 – Endomyocardial (eosinophilic) disease

What it is

This code identifies endomyocardial disease associated with eosinophilic involvement of the heart. Use it for documentation of myocardial or endocardial damage linked to eosinophilic infiltration, not for nonspecific cardiomyopathy.

Clinical signs

Clinical features may include restrictive cardiac findings, heart failure symptoms, or evidence of endocardial fibrosis. Clinical features vary; refer to documentation.

When to use this code

Use I42.3 when the provider documents endomyocardial disease, eosinophilic endomyocardial disease, or a similar confirmed diagnosis. It is appropriate when the record clearly links the cardiac disorder to eosinophilic involvement. If the note only says cardiomyopathy or myocarditis, check documentation.

Do not use for

Do not use this code for general cardiomyopathy without eosinophilic or endomyocardial specificity. Do not assign it when the diagnosis is uncertain or when the record describes a different cardiac condition.

Coding tip

Look for explicit provider wording tying the heart disease to eosinophilic endomyocardial involvement before assigning I42.3.

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