ICD-10 Code B57.40 – Chagas’ disease with nervous system involvement, unspecified (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code B57.40 – Chagas’ disease with nervous system involvement, unspecified
What it is
This code identifies Chagas’ disease caused by Trypanosoma cruzi when the nervous system is involved, but the affected site is not specified. Use it when the record confirms neurologic involvement without further detail.
Clinical signs
Clinical features vary; refer to documentation. Neurologic findings may include central or peripheral nervous system manifestations, but the chart should specify Chagas’ disease and some form of nervous system involvement.
When to use this code
Use B57.40 when the provider documents Chagas’ disease with neurologic involvement and does not name the exact nervous system site. It also fits when the note is clear about nervous system involvement but remains nonspecific.
Do not assume neurologic disease from travel history, exposure, or positive serology alone. If the documentation names a specific nervous system manifestation, check whether a more detailed code is supported.
Do not use for
Do not use this code for Chagas’ disease without nervous system involvement, or when another organ system is documented instead. Check documentation if the neurologic involvement is uncertain.
Coding tip
Verify that both Chagas’ disease and nervous system involvement are documented before assigning B57.40.