ICD-10 Code B57.4 – Chagas’ disease (chronic) with nervous system involvement (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code B57.4 – Chagas’ disease (chronic) with nervous system involvement
What it is
This code identifies chronic Chagas disease when Trypanosoma cruzi infection has affected the nervous system. Use it for documented neurologic involvement linked to chronic infection.
Clinical signs
Clinical features vary; refer to documentation. Neurologic involvement may include signs of central or peripheral nervous system disease, such as weakness, sensory changes, or other neurologic deficits attributed to chronic Chagas disease.
When to use this code
Use B57.4 when the record clearly states chronic Chagas disease with nervous system involvement. It fits cases where the clinician documents neurologic complications as part of the chronic infection. If the note only says Chagas disease without nervous system involvement, check documentation.
Do not use for
Do not use this code for acute Chagas disease or chronic Chagas disease limited to the heart or digestive system. Do not assign it when nervous system involvement is suspected but not documented.
Coding tip
Confirm both chronic Chagas disease and nervous system involvement are explicitly documented before assigning B57.4.